Syphilis Resources for Providers

Cases are Rising

Syphilis infections are on the rise in North Carolina. Syphilis can affect anyone, but is currently rising in women and men who have sex with women. This has led to an alarming increase in cases of congenital syphilis.

NCDHHS is working to improve access to syphilis testing, as well as community awareness about this growing epidemic, so that more people can have access to information and treatment.

On this page


Increase in congenital syphilis cases

From 2022 to 2023

Chart shows an increase in congenital syphilis cases in North Carolina over time, from 1 in 2012 to 74 in 2023.

2023 data is preliminary and may be incomplete.
More North Carolina Syphilis Data


News Releases and Memos

News Release (2/21/24): North Carolina Leads the Way in Expanding Access to Treatment for Syphilis

News Release (12/15/23): North Carolina Joins Southeastern States in Partnership to Combat the Surge in Congenital Syphilis Infections

Provider Memo (11/9/23): Continued Rise in Female and Congenital Syphilis Infections


Your Role as a Provider

As a clinician, you play an important role in preventing syphilis and congenital syphilis. Here's how you can do your part:


Information Specific to Congenital Syphilis 

Congenital syphilis is preventable by early detection and rapid treatment of the mother's infection. All pregnant women should be screened at least three times during pregnancy, irrespective of clinical signs (syphilis can be asymptomatic) or perceived risk.

Screenings Required By Law

North Carolina public health law requires healthcare providers screen all pregnant women for syphilis:

  • at the first prenatal visit, and
  • between 28-30 weeks’ gestation, and
  • at delivery. 

North Carolina Case Review Findings

Findings from a review of congenital syphilis cases in North Carolina from 2016 to 2022 indicate infants end up with congenital syphilis when:

  • There is no or late entry of pregnant women into prenatal care.
  • There was prenatal care but incomplete syphilis testing during pregnancy.
  • Mother received delayed, no, or inadequate treatment for her stage of syphilis infection.
  • The exposed newborn was not appropriately evaluated or treated at birth for congenital syphilis.


Materials to Share

Find social media graphics, brochures, flyers, posters, rack cards and more:

Get Free Materials


Links to Other Resources

Tab/Accordion Items