Acute Flaccid Myelitis (AFM)

Acute flaccid myelitis, also known as AFM, is a rare but serious neurological condition that primarily affects young children. 

AFM has been tracked nationwide since 2014 and became reportable in North Carolina in 2020. There has not been a single virus identified that causes AFM. Several different viruses can cause AFM, but one of the most common causes seems to be an enterovirus commonly referred to as EV-D68.

Read more about reportable diseases in North Carolina.

Signs and Symptoms

  • Sudden leg or arm weakness following a respiratory illness
  • Reduction in muscle tone
  • Loss of arm or leg reflexes
  • Facial droop
  • Difficulty moving the eyes
  • Difficulty swallowing
  • Slurred speech

Most (90%) cases of AFM occur in young children. It is most common in the fall, when respiratory viruses begin to circulate.

Prevention

  • Since the source of AFM is still unknown, standard precautions that lower the risk of getting a virus is the best prevention for AFM. These standard precautions include:
    • Wash your hands often with soap and water for at least 20 seconds.
    • Avoid touching your face with unwashed hands.
    • Avoid close contact with people who are sick.
    • Stay up to date on recommended vaccinations.
  • You can lower the chance of spreading a virus by:
    • Clean and disinfect frequently touched surfaces, like toys, mobile devices, and doorknobs.
    • Cover coughs and sneezes with a tissue or upper shirt sleeve, not hands.
    • Stay at home if you or your child are sick.

More tips for preventing AFM (CDC)

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This page was last modified on 06/18/2026